Wilson, a Democrat, says she hopes to challenge Sen. Orrin Hatch, a Republican who has said he intends to seek an eighth term.
"Over the past few months, I have been overwhelmed by the encouragement to run by Utahns who are desperate for change in Washington," Wilson said in a statement. "They are tired of the bickering and recognize the bipartisan successes I have had working locally."
Wilson, the daughter of former three-term Salt Lake City Mayor and one-time Hatch challenger Ted Wilson, is in her second six-year term on the County Council and formerly served as chief of staff to the late Rep. Bill Orton, D-Utah.